Trypsin Gold, mass spectrometry grade, has been manufactured to provide maximum specificity. Lysine residues in the porcine trypsin have been modified by reductive methylation, yielding a highly active and stable molecule that is extremely resistant to autolytic digestion. The specificity of the purified trypsin is further improved by TPCK treatment, which inactivates chymotrypsin. The treated trypsin is then purified by affinity chromatography and lyophilised.
- Each lot qualified by mass spectrometry to ensure compatibility with applications and instrumentation
- Chymotrypsin activity eliminated for distinct, consistent data
- Digest in gel, or in solution